PerClot potentially negatively impacts which phase of wound healing?

• A. Inflammatory phase
• B. Proliferative phase
• C. Maturation phase
• D. Hemostatic phase

Answer: (A)

During wound healing, the inflammatory phase is the initial response where immune cells clear debris and fight infection. PerClot, as a topical hemostatic agent, can irritate tissue or leave behind residues that act as a foreign body. This tends to trigger a stronger and sometimes prolonged inflammatory response. Because inflammation is meant to be temporary, an exaggerated or extended inflammatory reaction delays the switch to the proliferative phase (new tissue formation) and the subsequent maturation phase (remodeling). So PerClot can negatively impact the inflammatory phase by amplifying and extending the inflammatory response, hindering overall healing.