What are the components of Floseal?

• A. Porcine Gelatin Matrix + Sodium Chloride (with or without Human Thrombin)
• B. Bovine Gelatin Matrix + Human Fibrinogen
• C. Human Gelatin Matrix + Sodium Chloride
• D. Bovine Gelatin Matrix + Human Thrombin + Sodium Chloride

Answer: (D)

Floseal is a flowable hemostatic that combines a bovine-derived gelatin matrix with a human thrombin component, delivered in saline. The gelatin matrix provides a physical scaffold and helps tamponade bleeding, while the thrombin activates the clotting cascade by converting fibrinogen to fibrin to form a stable clot at the site of application. The saline (sodium chloride) serves as the vehicle to reconstitute and deliver the mixture smoothly. So the full, correct formulation includes a bovine gelatin matrix, human thrombin, and sodium chloride. Porcine gelatin, fibrinogen instead of thrombin, or a non-saline matrix would not match Floseal’s actual composition.