Which product uses collagen as its base material?

• A. Floseal
• B. Surgiflo
• C. Avitene Flowable
• D. Surgicel Powder

Answer: (C)

Collagen-based hemostats use collagen as the underlying material to promote platelet activation and clot formation. Avitene Flowable is a microfibrillar collagen hemostatic agent delivered as a flowable paste, so its base material is collagen. The other products rely on different base materials: Floseal and Surgiflo are gelatin matrices (often with thrombin) that provide a physical scaffold to aid coagulation, while Surgicel Powder is oxidized cellulose that also promotes clotting but is not collagen. So Avitene Flowable is the product that uses collagen as its base material.